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FOX04-DRI 10mg

FOX04-DRI 10mg

£79.99 GBP

FOX04-DRI (Forkhead box O4 - D-Retro-Inverso peptide) is a synthetic peptide studied primarily for its potential role in targeting and clearing senescent (aging) cells, making it a focus in cellular senescence research.

Purpose and Mechanism:

FOX04-DRI functions as a senolytic agent. It achieves this by selectively disrupting the interaction between the FOXO4 transcription factor and $\text{p}53$ within senescent cells. This disruption interferes with the survival pathways that aging cells use to avoid apoptosis (programmed cell death). By inducing apoptosis only in the dysfunctional senescent cells, FOX04-DRI aims to reduce the burden of these cells on tissues.

Key Research Benefits:

  • Senolytic Action: Studied for its potential to selectively eliminate senescent cells, reducing cellular aging markers.

  • Tissue Regeneration: Research suggests that removing senescent cells may help improve the function and regenerative capacity of surrounding healthy tissue.

  • Longevity Research: Highly researched for its applications in addressing age-related cellular decline and associated chronic conditions.

Product Specification:

This product is supplied as 10mg of high-purity FOX04-DRI.

Note: This product is sold strictly for research purposes only.

Sequence: Trp-Glu-Lys-Lys-Lys-Arg-Arg-Arg-Gly-Arg-Phe-Phe-Ser-Cys-His-Gln-Asn-Cys-Pro-Val-Asn-Ser (D-retro-inverso)

Molecular Formula: C₁₀₉H₁₇₃N₃₇O₂₃S₂

Molecular Weight: ~2660 g/mol

Peptide Class: Senolytic D-retro-inverso peptide

Purity: ≥ 99%

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